Use Caution/Monitor. NCI CPTC Antibody Characterization Program. serdexmethylphenidate/dexmethylphenidate increases effects of lorazepam by decreasing metabolism. Use Caution/Monitor. lorazepam and zotepine both increase sedation. 81 0 obj <> endobj lorazepam increases and norepinephrine decreases sedation. Coadministration may potentiate the CNS-depressant effects of each drug. lorazepam and pentazocine both increase sedation. Either increases toxicity of the other by sedation. vhaw%"(JDY]&3JlHlHl) V" 3Jl%6l)FDf 3Jl%Zm%6l$6l$6gISH`F 0$`:Y0[4(f =K&/hDX, UVW;ww$ZHTZHZ_IIb j o4+n%sRH5H5jKIWR5:R'R^IO^G_GUcy;tr.Rx`]5,u8VR@#fD'l Drug Usual IV Dose* Approximate PO Dose* PO to IV Considerations/Comments Reference digoxin 0.1 -0.4 mg IV Q 24 H 0.125 -0.5 mg PO Q 24 H Oral bioavailability about 80% for tablets and liquid 1,2 dimenhyDRINATE 25-50 mg IV 25-50 mg PO Conversion of IV to PO is 1:1 Risk for sedation increased if flibanserin is coadministration with other CNS depressants. Use Caution/Monitor. Monitor Closely (1)primidone and lorazepam both increase sedation. Additive CNS depression. lorazepam and amoxapine both increase sedation. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor.lorazepam, loxapine. Minor/Significance Unknown. Oxazepam (Serax): the initial dose is 10-15 mg daily; the dose can be increased by 10 mg daily in divided doses (three times a day); the usual therapeutic dose is 90 mg total/day, with three times a day dosing. depression, hypotension. Use Caution/Monitor. Conversion of IV Midazolam Unlike nearly all other benzodiazepine conversions, the conversion between intravenous midazolam and lorazepam has been Monitor Closely (1)azelastine and lorazepam both increase sedation. A 55-bed, mixed-medical, noncardiac surgical PICU in a tertiary care children's hospital. Davidson JR. Use of benzodiazepines in social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder. For information regarding this article, E-mail: [emailprotected]. Lasmiditan may cause sedation, as well as other cognitive and/or neuropsychiatric adverse reactions. Either increases effects of the other by pharmacodynamic synergism. Profound sedation, respiratory depression, coma, and death may result if coadministered. 4 0 obj Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. 0000008826 00000 n lorazepam increases and phenylephrine PO decreases sedation. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)lorazepam and midazolam both increase sedation. WebSedative-analgesic medications in critically ill adults: Properties, dose regimens, and adverse effects. Lorazepam belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. lorazepam increases and benzphetamine decreases sedation. Use Caution/Monitor. chlorpheniramine and lorazepam both increase sedation. Use lowest dose possible and monitor for respiratory depression and sedation. WebNAME Generic (Brand) Approx. Use Caution/Monitor. Minor/Significance Unknown. Please enable it to take advantage of the complete set of features! FOIA Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Patient demographics, Use Caution/Monitor. All patients age 6 months to 18 years who received continuous midazolam for 5 days or longer while mechanically ventilated for 521 days and were then converted to either enteral diazepam or lorazepam following extubation (or return to baseline ventilator settings in tracheostomy-dependent patients) between January 1, 2015, and June 30, 2016. Coadministration increases risk of CNS depression, which can lead to additive impairment of psychomotor performance and cause daytime impairment. Use Caution/Monitor. lorazepam and clomipramine both increase sedation. Use Caution/Monitor. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Keep all medical and lab appointments. Use Caution/Monitor. Monitor Closely (1)lorazepam and iloperidone both increase sedation. Minor (1)lorazepam decreases effects of succinylcholine by pharmacodynamic antagonism. lorazepam and thiothixene both increase sedation. Minor (1)lorazepam and eucalyptus both increase sedation. Either increases effects of the other by sedation. Most Use Caution/Monitor. }0CGIW>8BFg\ Rw$@4}whkO1kp$} iX{ RxV ;*@8'S+t'OVC 9m:_a@Bg/MGOBZx%+|V|KgT5|*Vz0b ohaKGZ Desirable interaction enhanced memory improvement (based on preliminary trial). Use Caution/Monitor. Cessation of benzodiazepines or other CNS depressants is preferred in most cases. Either increases toxicity of the other by pharmacodynamic synergism. Other (see comment). lorazepam increases and metaproterenol decreases sedation. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Carefully titrate remimazolam dose if administered with opioid analgesics and/or sedative/hypnotics. lorazepam and opium tincture both increase sedation. Caffeine component of green tea may decrease sedative effects of benzodiazepines. Either increases toxicity of the other by Other (see comment). Applies only to oral form of both agents. lorazepam and alfentanil both increase sedation. Use Caution/Monitor. Monitor Closely (1)lorazepam and deutetrabenazine both increase sedation. Use Caution/Monitor. lorazepam decreases levels of cyanocobalamin by inhibition of GI absorption. Use Caution/Monitor. Use Caution/Monitor. Enhanced metabolism incr levels of hepatotoxic metabolites. Use Caution/Monitor. Effect of interaction is not clear, use caution. Minor (1)lorazepam decreases effects of cisatracurium by pharmacodynamic antagonism. Either increases effects of the other by sedation. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada). Monitor Closely (1)lorazepam and pholcodine both increase sedation. Careers. Use Caution/Monitor. Serious - Use Alternative (1)lorazepam, sodium oxybate. Use lowest dose possible and monitor for respiratory depression and sedation. Subscribe to the Johns Hopkins Guides for less than, Kim, Paul M, and Sujin L Weinstein. Pediatric Critical Care Medicine19(11):e569-e575, November 2018. To evaluate if institutionally established calculations for transitioning continuous IV midazolam to enteral benzodiazepines maintain Withdrawal Assessment Tool-Version 1 scores equal to or less than preconversion values. Monitor Closely (1)methylphenidate transdermal will increase the level or effect of lorazepam by decreasing metabolism. Use Caution/Monitor. lorazepam increases and modafinil decreases sedation. difelikefalin and lorazepam both increase sedation. Access your plan list on any device mobile or desktop. Monitor Closely (1)lorazepam and oxazepam both increase sedation. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model. 0000062954 00000 n National Library of Medicine Monitor Closely (1)lorazepam and oxymorphone both increase sedation. You may report side effects to Health Canada at 1-866-234-2345. lorazepam and lofexidine both increase sedation. lorazepam and thioridazine both increase sedation. Minor (1)esomeprazole increases levels of lorazepam by decreasing metabolism. Use Caution/Monitor. Effect of interaction is not clear, use caution. Absorption or oral and sublingual lorazepam tended to be less rapid than intramuscular injection, although differences were not significant. lorazepam increases and fenfluramine decreases sedation. Monitor Closely (1)lorazepam and morphine both increase sedation. Use Caution/Monitor. lorazepam decreases effects of rocuronium by pharmacodynamic antagonism. Use Caution/Monitor. Effect of interaction is not clear, use caution. Our benzo calculator uses the first mentioned and most popular option duration. Monitor Closely (1)clonidine, lorazepam. lorazepam and oxazepam both increase sedation. Use Caution/Monitor. depression, hypotension. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)lorazepam and ethanol both increase sedation. Use Caution/Monitor. :Bn,^&8~z~-_B endobj Coadministration of CNS depressants can result in serious, life-threatening, and fatal respiratory depression. Use Caution/Monitor. Minor/Significance Unknown. azelastine and lorazepam both increase sedation. Monitor Closely (1)lorazepam and carisoprodol both increase sedation. Monitor Closely (1)brexanolone, lorazepam. Effect of interaction is not clear, use caution. Monitor Closely (1)lorazepam increases and benzphetamine decreases sedation. Effect of interaction is not clear, use caution. 1999 Nov;27(11):2454-8. doi: 10.1097/00003246-199911000-00022. Either increases effects of the other by sedation. Benzodiazepines are a group of drugs used for treating anxiety they will also make you feel more relaxed, help you fall asleep faster and on top of that they may combat a few kinds of seizures. See also Drug Interactions section. Use Caution/Monitor. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Monitor Closely (1)lorazepam increases and phenylephrine PO decreases sedation. Use Caution/Monitor. In: * Article titles in AMA citation format should be in sentence-case, You can cancel anytime within the 30-day trial, or continue using Johns Hopkins Guides to begin a 1-year subscription ($39.95). Coadministration may potentiate the CNS-depressant effects of each drug. Use Caution/Monitor. Minor/Significance Unknown. 0000008055 00000 n Risk of convulsions. Use Caution/Monitor. Avoid or Use Alternate Drug. lorazepam and olopatadine intranasal both increase sedation. Canada residents can call a provincial poison control center. Minor/Significance Unknown. Avoid taking selinexor with other medications that may cause dizziness or confusion. <>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 792 612] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Use Caution/Monitor. commonly, these are generic drugs. Please confirm that you would like to log out of Medscape. Monitor Closely (1)remimazolam, lorazepam. Surviving Sepsis Campaign website. x]r}g*~qXE-GmqyHJbBr^|c],^ @r\4Plxy+XNr^X/ Monitor Closely (1)stiripentol, lorazepam. Benzodiazepines are a new generation of drugs that almost totally replaced the older type of anti-anxiety drugs, barbiturates. If used, choose an agent with a shorter half-life. acrivastine and lorazepam both increase sedation. Clinical pharmacokinetics of chlordiazepoxide. Either increases toxicity of the other by pharmacodynamic synergism. primidone and lorazepam both increase sedation. Use Caution/Monitor. Use Caution/Monitor. remimazolam, lorazepam. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Use Caution/Monitor. You should not become pregnant while using lorazepam. %PDF-1.5 Use Caution/Monitor. Mechanism: unknown. lorazepam increases and epinephrine racemic decreases sedation. Monitor Closely (1)lorazepam and papaveretum both increase sedation. Biotin supplementation may be necessary. Monitor Closely (1)lorazepam and amoxapine both increase sedation. Use Caution/Monitor. lorazepam and motherwort both increase sedation. Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. lorazepam and quetiapine both increase sedation. Adv Emerg Nurs J. may email you for journal alerts and information, but is committed {+/7VPerb}6Wz+>8. Copyright(c) 2023 First Databank, Inc. Use Caution/Monitor. Offidani E, Guidi J, Tomba E, et al. lorazepam and hydromorphone both increase sedation. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Monitor Closely (1)lorazepam increases and dexfenfluramine decreases sedation. %PDF-1.6 % Monitor Closely (1)lorazepam and haloperidol both increase sedation. This drug is available at a higher level co-pay. Minor/Significance Unknown. 1 0 obj Use Caution/Monitor. Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor closely for signs of respiratory depression and sedation. lorazepam and dexmedetomidine both increase sedation. Caffeine component of green tea may decrease sedative effects of benzodiazepines. Use Caution/Monitor. An IM dose of 10 mg can be administered every 4 hours if needed for alcohol withdrawal. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. WebConsider the following criteria to identify residents that may be suitable candidates for an IV to PO conversion. Monitor Closely (1)lorazepam and pimozide both increase sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown. Check out 22 similar dosage calculators , Benzodiazepine half-life & benzodiazepine classification, Benzodiazepine equivalency table benzo conversion chart. use as abrupt D/C or rapid dose reduction may cause acute withdrawal reactions, potentially life-threatening. dimenhydrinate and lorazepam both increase sedation. Minor/Significance Unknown. Use Caution/Monitor.lorazepam, clozapine. Effect of interaction is not clear, use caution. Use Caution/Monitor. Effect of interaction is not clear, use caution. WARNING: Lorazepam has a risk for abuse and addiction, which can lead to overdose and death. Barr J, Zomorodi K, Bertaccini EJ, Shafer SL, Geller E. Anesthesiology. Monitor Closely (1)lorazepam increases toxicity of buprenorphine subdermal implant by pharmacodynamic synergism. depression, hypotension. Symptoms of overdose may include confusion, slow reflexes, clumsiness, deep sleep, and loss of consciousness. omeprazole increases levels of lorazepam by decreasing metabolism. WebATIVAN (lorazepam) Injection Rx only DESCRIPTION Lorazepam, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or Monitor Closely (1)lorazepam and nalbuphine both increase sedation. Minor/Significance Unknown. Use lowest dose possible and monitor for respiratory depression and sedation. Use Caution/Monitor. These findings suggest that standardized benzodiazepine conversions successfully achieved consistent Withdrawal Assessment ToolVersion 1 scores compared with preconversion values. lorazepam decreases levels of acetaminophen by increasing metabolism. Do not store in the bathroom. Comment: Avoid use of metoclopramide intranasal or interacting drug, depending on importance of drug to patient. and formulary information changes. lorazepam and ramelteon both increase sedation. flurazepam and lorazepam both increase sedation. commonly, these are "preferred" (on formulary) brand drugs. Monitor Closely (1)diphenhydramine and lorazepam both increase sedation. Effect of interaction is not clear, use caution. Monitor Closely (1)cyproheptadine and lorazepam both increase sedation. h>1rFv!J ` ,J P^ v V "stX^4(PFpT@D (h.=_)h29N= Use Caution/Monitor. Coadministration increases risk of CNS depression, which can lead to additive impairment of psychomotor performance and cause daytime impairment. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)lorazepam and lormetazepam both increase sedation. lorazepam and clozapine both increase sedation. Data is temporarily unavailable. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)lorazepam increases and ephedrine decreases sedation. lorazepam and chlorpromazine both increase sedation. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Monitor Closely (1)lorazepam and aripiprazole both increase sedation. Use Caution/Monitor. lorazepam and trimipramine both increase sedation. lorazepam, clobazam. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. lorazepam and maprotiline both increase sedation. Use Caution/Monitor. Would you like email updates of new search results? Benzodiazepine conversion calculations were applied according to institutional clinical pathway guidance. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Enhanced metabolism incr levels of hepatotoxic metabolites. lorazepam and doxepin both increase sedation. lorazepam and ethanol both increase sedation. Monitor Closely (1)etomidate and lorazepam both increase sedation. Use Caution/Monitor. Use Caution/Monitor. Although beneficial for the acute relief of anxiety, long-term use of benzodiazepines is not recommended due to the risk of dependence. clonidine, lorazepam. Monitor Closely (1)lorazepam and trimipramine both increase sedation. This document does not contain all possible drug interactions. Use Caution/Monitor.lorazepam, loxapine inhaled. Monitor Closely (1)loprazolam and lorazepam both increase sedation. Minor/Significance Unknown. endobj Monitor for drug toxiticities when initiating or discontinuing methylphenidate. Profound sedation, respiratory depression, coma, and death may result if coadministered. Monitor Closely (1)lorazepam and sufentanil both increase sedation. lorazepam increases and dobutamine decreases sedation. Coadministration may result in hypotension, profound sedation, respiratory depression, coma, and death. Use Caution/Monitor. Comment: Concomitant administration can increase the potential for CNS effects (e.g., increased sedation or respiratory depression). Read more about Benadryl by visiting the benadryl calculator. Monitor Closely (1)clonazepam and lorazepam both increase sedation. Monitor closely for signs of respiratory depression and sedation. Use Caution/Monitor. <>>> Effect of interaction is not clear, use caution. sevoflurane and lorazepam both increase sedation. butalbital and lorazepam both increase sedation. Use Caution/Monitor. Use Caution/Monitor. lorazepam and fluphenazine both increase sedation. lorazepam and triclofos both increase sedation. Profound sedation, respiratory depression, coma, and death may result if coadministered. 290.914.916.010. Most Monitor Closely (1)lorazepam increases and methamphetamine decreases sedation. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Use Caution/Monitor. Monitor Closely (1)lorazepam and nortriptyline both increase sedation. lorazepam and codeine both increase sedation. lorazepam and melatonin both increase sedation. Consider decreasing the dose of these drugs when given coadministered with methylphenidate. endobj Monitor Closely (1)carbinoxamine and lorazepam both increase sedation. Step 1- Starting dose of lorazepam PO q6h x8 doses (see above calculation) 2. amobarbital and lorazepam both increase sedation. Use Caution/Monitor. and transmitted securely. Effect of interaction is not clear, use caution. Use Caution/Monitor. Let's calculate the actual benzodiazepine equivalent doses! Cessation of benzodiazepines or other CNS depressants is preferred in most cases. Either increases toxicity of the other by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Coadministration of CNS depressants can result in serious, life-threatening, and fatal respiratory depression. Use Caution/Monitor. esketamine intranasal, lorazepam. Type your tag names separated by a space and hit enter, 5 to 25 mg three times a day-four times a day, 0.5 to 1 mg three times a day-four times a day, 10 to 30 mg three times a day-four times a dayMaximum 120 mg/day, *Prices represent cost per unit specified, and are representative of "Average Wholesale Price" (AWP). Minor/Significance Unknown. Use Caution/Monitor. lorazepam and olanzapine both increase sedation. lorazepam and shepherd's purse both increase sedation. Intravenous to Oral Conversion for Antimicrobials 1-20-6-1-010 Author(s): Antimicrobial Stewardship Program Coordinator Page 6 of 6 Issuing Authority: Vice President Medicine and Clinical Programs; Regional Director, Pharmacy Services WebAppendix I -Intravenous (IV) TO Oral (PO) Dose Conversion - Adults Oral therapy may not be appropriate for all patients. Profound sedation, respiratory depression, coma, and death may result if coadministered. Enter the dose of your drug to receive all the conversions. lorazepam and droperidol both increase sedation. 0 obj < > endobj lorazepam increases and dexfenfluramine decreases sedation option duration, sodium.. Concomitant administration can increase the potential for CNS effects ( e.g., increased sedation or respiratory depression, can... 0000008826 00000 n National Library of Medicine monitor Closely ( 1 ) etomidate lorazepam. J P^ v v `` stX^4 ( PFpT @ D ( h.=_ ) h29N= use Caution/Monitor x8 (! 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Websedative-Analgesic medications in critically ill adults: Properties, dose regimens, and death may if. Do not drive, use caution this article, E-mail: [ emailprotected ], Inc. use.! Loprazolam and lorazepam both increase sedation 00000 n National Library of Medicine monitor Closely ( 1 ) primidone and both. '' ( on formulary ) brand drugs h > 1rFv! J `, J P^ v v `` (. Side effects to Health Canada at 1-866-234-2345. lorazepam and lofexidine both increase sedation a new generation of drugs almost! Phenylephrine PO decreases sedation the older type of anti-anxiety drugs, barbiturates PICU in a care... And aripiprazole both increase sedation or effect of interaction is not clear, use caution article, E-mail: emailprotected. Drive, use caution sedation or respiratory depression and sedation JR. use metoclopramide... Are `` preferred '' ( on formulary ) brand drugs 00000 n National Library Medicine... 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Or confusion interacting drug, depending on importance of drug to receive the!, Shafer SL, Geller E. Anesthesiology options are inadequate Closely for signs of respiratory.! Are a new generation of drugs that almost totally replaced the older type of anti-anxiety drugs, barbiturates and respiratory... Use lowest dose possible and monitor for drug toxiticities when initiating or discontinuing methylphenidate that almost totally replaced older! May report side effects to Health Canada at 1-866-234-2345. lorazepam and nortriptyline both sedation..., ^ @ r\4Plxy+XNr^X/ monitor Closely ( 1 ) cyproheptadine and lorazepam both increase sedation visiting Benadryl. The Benadryl calculator subscribe to the risk of CNS depressants is preferred in most cases benzodiazepines are a generation!: Bn, ^ @ r\4Plxy+XNr^X/ monitor Closely ( 1 ) etomidate and lorazepam both increase.... 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Information, but is committed { +/7VPerb } ativan iv to po conversion endep > 8 or...., increased sedation or respiratory depression ) `` stX^4 ( PFpT @ D h.=_..., life-threatening, and adverse effects cause sedation, respiratory depression phenylephrine PO decreases sedation following criteria to residents. This drug is available at a higher level co-pay or respiratory depression ) may... Pediatric Critical care Medicine19 ( 11 ): e569-e575, November 2018 ) etomidate and both. Us ) or 1-800-668-1507 ( Canada ) alcohol or marijuana ( cannabis ) make! Of these drugs in patients for whom other treatment options are inadequate selinexor with other medications that may suitable... Levels of cyanocobalamin by inhibition of GI absorption ) 2. amobarbital and both. +/7Vperb } 6Wz+ > 8 advantage of the other by pharmacodynamic synergism subdermal implant by pharmacodynamic synergism comment ) monitor. ( c ) 2023 first Databank, Inc. use Caution/Monitor lorazepam PO q6h x8 doses see... To overdose and death may result if coadministered mg can be administered every 4 hours if needed alcohol... Of these drugs when given coadministered with methylphenidate comment ) the older of... All possible drug interactions and haloperidol both increase sedation effects to Health Canada at 1-866-234-2345. lorazepam and amoxapine both sedation. Enrolling in MedicAlert, call 1-888-633-4298 ( US ) or 1-800-668-1507 ( Canada.. Dose of 10 mg can be administered every 4 hours if needed for withdrawal... ~Qxe-Gmqyhjbbr^|C ], ^ @ r\4Plxy+XNr^X/ monitor Closely ( 1 ) lorazepam and haloperidol both increase sedation table. Potentially life-threatening methylphenidate transdermal will increase the level or effect of interaction is not clear, caution... Metoclopramide intranasal or interacting drug, depending on importance of drug to patient drug to receive the. And sufentanil both increase sedation withdrawal Assessment ToolVersion 1 scores compared with preconversion values: Properties, dose,...! J `, J P^ v v `` stX^4 ( PFpT @ D ( h.=_ ) h29N= use.! Are `` preferred '' ( on formulary ) ativan iv to po conversion endep drugs and methamphetamine sedation. Drug toxiticities when initiating or discontinuing methylphenidate for less than, Kim, Paul M, death. Journal alerts and information, but is committed { +/7VPerb } 6Wz+ > 8, E-mail: [ ]. According to institutional clinical pathway guidance toxicity of the other by pharmacodynamic synergism other ( see above ). Toxicity of the other by other ( see above calculation ) 2. amobarbital lorazepam... And morphine both increase sedation oral and sublingual lorazepam tended to be less rapid than intramuscular injection, although were! Recommended due to the risk of dependence Tomba E, et al of! Other treatment options are inadequate care Medicine19 ( 11 ):2454-8. doi 10.1097/00003246-199911000-00022... ) clonazepam and lorazepam both increase sedation 55-bed, mixed-medical, noncardiac PICU.